The hotels will be managed by RBH (formerly known as Redefine|BDL Hotels).
The new Doubletree by Hilton hotels will be located in Stratford-upon-Avon, Oxford, Glasgow, Cambridge and Forest Pines in Yorkshire.
The hotels are expected to start welcoming guests later this year.
DoubleTree by Hilton Forest Pines Hotel & Golf Resort (pictured) with 188 bedrooms is set in 190 acres of Yorkshire woodland and includes meeting and events space plus a 27-hole golf course, a spa and health club.
DoubleTree by Hilton Oxford Belfry with 154 rooms is set 17 acres of landscaped gardens with good access to the centre of Oxford. The hotel has a range of events space plus a spa and health club.
DoubleTree by Hilton Glasgow Westerwood Hotel & Golf Resort has 148 bedrooms, a spa, health club and two restaurants plus an 18-hole golf course and meeting space for up to 400 delegates.
DoubleTree by Hilton Cambridge Belfry with 120 bedrooms is locatedon the outskirts of Cambridge boasting lakeside vistas, a spa and health club and modern meeting space.
DoubleTree by Hilton Stratford-upon-Avon with 102 bedrooms is situated in the heart of Stratford-upon-Avon. It features a fine dining restaurant and a fully equipped gym.
The five additions will take the number of Doubletree by Hilton hotels in the UK above the 50-mark.